In this Article

• What is fentanyl buccal (Fentora)?
• What are the possible side effects of fentanyl buccal (Fentora)?
• What is the most important information I should know about fentanyl buccal (Fentora)?
• What should I discuss with my healthcare provider before using fentanyl buccal (Fentora)?
• How should I use fentanyl buccal (Fentora)?
• What happens if I miss a dose (Fentora)?
• What happens if I overdose (Fentora)?
• What should I avoid while using fentanyl buccal (Fentora)?
• What other drugs will affect fentanyl buccal (Fentora)?
• Where can I get more information?

What happens if I miss a dose (Fentora)?

Since fentanyl buccal is used on an as needed basis, you are not likely to miss a dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Fentora)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A fentanyl overdose can be fatal.

Overdose symptoms may include extreme weakness or dizziness, pinpoint pupils, cold and clammy skin, weak pulse, fainting, slow breathing (breathing may stop).

What should I avoid while using fentanyl buccal (Fentora)?

Do not use fentanyl with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Fentanyl may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Grapefruit and grapefruit juice may interact with fentanyl and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

What other drugs will affect fentanyl buccal (Fentora)?

Do not take fentanyl buccal with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Tell your doctor about all other medicines you use, especially:

• dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
• imatinib (Gleevec);
• isoniazid (for treating tuberculosis);
• St. John's wort;
• an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), rifapentine (Priftin), or telithromycin (Ketek);
• antifungal medicine such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
• an antidepressant such as nefazodone;
• heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Nifedical, Procardia), quinidine (Quin-G), verapamil (Calan, Covera, Isoptin, Verelan), and others;
• HIV medication such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Norvir, Kaletra); or
• seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).

This list is not complete and other drugs may interact with fentanyl buccal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about fentanyl buccal.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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