Fioricet with Codeine

Drug Description
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Fioricet with Codeine
(butalbital, acetaminophen, caffeine, and codeine phosphate) Capsule

DRUG DESCRIPTION

Fioricet® with Codeine (butalbital, acetaminophen, caffeine, and codeine phosphate) is supplied in capsule form for oral administration.

Each capsule contains the following active ingredients:

butalbital, USP.......................50 mg
acetaminophen, USP............325 mg
caffeine, USP........................40 mg
codeine phosphate, USP..........30 mg

Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula:

Fioricet with Codeine (butalbital) Structural Formula Illustration

C11H16N2O3                      molecular weight 224.26

Acetaminophen (4´-hydroxyacetanilide) is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

Fioricet with Codeine (acetaminophen) Structural Formula Illustration

C8H9NO2                      molecular weight 151.16

Caffeine (1,3,7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula:

Fioricet with Codeine (caffeine) Structural Formula Illustration

C8H10N4O2                       molecular weight 194.19

Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate) is a narcotic analgesic and antitussive. It has the following structural formula:

Fioricet with Codeine (codeine phosphate) Structural Formula Illustration

C18H24NO7P                      anhydrous molecular weight 397.37

Inactive Ingredients: colloidal silicon dioxide, magnesium stearate, pregelatinized starch. Gelatin capsules contain black iron oxide, D&C Red No. 33, FD&C Blue No. 1, gelatin, red iron oxide, and titanium dioxide. The capsules are printed with edible inks containing D&C Red No. 7 Calcium Lake, FD&C Blue No. 1 Aluminum Lake, and titanium dioxide.

Last updated on RxList: 4/15/2008

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