In this Article
- What other names is Flaxseed known by?
- What is Flaxseed?
- How does Flaxseed work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Flaxseed.
Flaxseed is sometimes tried for cancer because it is broken down by the body into chemicals called "lignans." Lignans are similar to the female hormone estrogen - so similar, in fact, that they compete with estrogen for a part in certain chemical reactions. As a result, natural estrogens seem to become less powerful in the body. Some researchers believe that lignans may be able to slow down the progress of certain breast cancers and other types of cancers that need estrogen to thrive.
For systemic lupus erythematosus (SLE), flaxseed is thought to improve kidney function by decreasing the thickness of blood, reducing cholesterol levels, and reducing swelling.
There is some concern that taking large amounts of flaxseed could block the intestines due to the bulk-forming laxative effects of flaxseed. Flaxseed should be taken with plenty of water to prevent this from happening.
Taking flaxseed extracts that contain lignans in concentrated form is POSSIBLY SAFE. Lignans are the chemicals in flaxseed that are thought to be responsible for many of the effects. Some clinical research shows that a specific flaxseed lignan extract (Flax Essence, Jarrow Formulas) can be safely used for up to 12 weeks.
Products that contain partially defatted flaxseed, which is flaxseed with less alpha-linolenic acid content, are available. Some men choose these products because they have heard that alpha-linolenic acid might raise their risk of getting prostate cancer. It's important to remember that the source of the alpha-linolenic acid is key. Alpha-linolenic acid from dairy and meat sources has been positively associated with prostate cancer. However, alpha-linolenic acid from plant sources, such as flaxseed, does not seem to affect prostate cancer risk. Men should not worry about getting alpha-linoleic acid from flaxseed. On the other hand, there is a concern that partially defatted flaxseed might raise triglyceride levels too much. Triglycerides are a type of blood fat.
Raw or unripe flaxseed is POSSIBLY UNSAFE. Flaxseed in these forms is thought to be poisonous.
Special Precautions & Warnings:Pregnancy and breast-feeding: Taking flaxseed by mouth during pregnancy is POSSIBLY UNSAFE. Flaxseed can act like the hormone estrogen. Some healthcare providers worry that this might harm the pregnancy, although to date there is no reliable clinical evidence about the effects of flaxseed on pregnancy outcomes. The effect of flaxseed on breast-fed infants is unknown at this time. Stay on the safe side, and don't use flaxseed if you are pregnant or breast-feeding.
Bleeding disorders: Flaxseed might slow clotting. This raises the concern that it could increase the risk of bleeding in people with bleeding disorders. Don't use it, if you have a bleeding disorder.
Diabetes: There is some evidence that flaxseed can lower blood sugar levels and might increase the blood sugar-lowering effects of some medicines used for diabetes. There is a concern that blood sugar could drop too low. If you have diabetes and use flaxseed, monitor your blood sugar levels closely.
Gastrointestinal (GI) obstruction: People with a bowel obstruction, a narrowed esophagus (the tube between the throat and the stomach), or an inflamed (swollen) intestine should avoid flaxseed. The high fiber content of flaxseed might make the obstruction worse.
Hormone-sensitive cancers or conditions: Because flaxseed might act somewhat like the hormone estrogen, there is some concern that flaxseed might make hormone-sensitive conditions worse. Some of these conditions include breast, uterine, and ovarian cancer; endometriosis; and uterine fibroids. However, some early laboratory and animal research suggests that flaxseed might actually oppose estrogen and might be protective against hormone-dependent cancer. Still, until more is known, avoid excessive use of flaxseed if you have a hormone-sensitive condition.
High triglyceride levels (hypertriglyceridemia): Partially defatted flaxseed (flaxseed with less alpha linolenic acid content) might increase triglyceride levels. If your triglyceride levels are too high, don't take flaxseed.
Low blood pressure (hypotension): Flaxseeds might lower diastolic blood pressure. Theoretically, taking flaxseeds might cause blood pressure to become too low in individuals with low blood pressure.
High blood pressure (hypertension): Flaxseeds might lower diastolic blood pressure. Theoretically, taking flaxseeds might cause blood pressure to become too low in individuals with high blood pressure who are taking blood pressure-lowering medication.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get breaking medical news.