"Medscape Medical News
March 19, 2013 -- People with low back pain may benefit from a hands-on treatment known as osteopathic manual therapy (OMT) more than they do from ultrasound therapy.
A new study suggests that OMT leads t"...
(cyclobenzaprine hydrochloride) Tablets
Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C20H21N•HCl and a molecular weight of 311.9. It has a melting point of 217°C, and a pKa of 8.47 at 25°C. It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents. If aqueous solutions are made alkaline, the free base separates. Cyclobenzaprine HCl is designated chemically as 3-(5H -dibenzo[a,d] cyclohepten-5ylidene)-N, N-dimethyl-1-propanamine hydrochloride, and has the following structural formula:
FLEXERIL 5 mg (Cyclobenzaprine HCl) is supplied as a 5 mg tablet for oral administration.
FLEXERIL 10 mg (Cyclobenzaprine HCl) is supplied as a 10 mg tablet for oral administration.
FLEXERIL 5 mg (Cyclobenzaprine HCl) tablets contain the following inactive ingredients: lactose hydrous, pre-gelatinized starch, corn starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, titanium dioxide, Yellow D&C #10 Aluminum Lake HT, Yellow FD&C #6 Aluminum Lake, and carnauba wax.
FLEXERIL 10 mg (Cyclobenzaprine HCl) tablets contain the following inactive ingredients: lactose hydrous, pre-gelatinized starch, corn starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, titanium dioxide, yellow iron oxide, and carnauba wax.
What are the possible side effects of cyclobenzaprine (Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using cyclobenzaprine and call your doctor at once if you have any of these serious side effects:
- fast, pounding, or uneven heartbeats;
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- sudden numbness or weakness, especially on one side of the body;
- sudden headache,...
What are the precautions when taking cyclobenzaprine hcl (Flexeril)?
Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, overactive thyroid (hyperthyroidism), heart problems (such as irregular heartbeat, heart block, heart failure, recent heart attack), difficulty urinating (such as due to an enlarged prostate), glaucoma.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic...
Last reviewed on RxList: 4/29/2013
This monograph has been modified to include the generic and brand name in many instances.
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Chronic Pain/Back Pain
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