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Details with Side Effects
FLONASE (fluticasone propionate) Nasal Spray is indicated for the management of the nasal symptoms of seasonal and perennial allergic and nonallergic rhinitis in adults and pediatric patients 4 years of age and older.
Safety and effectiveness of FLONASE (fluticasone propionate) Nasal Spray in children below 4 years of age have not been adequately established.
DOSAGE AND ADMINISTRATION
Patients should use FLONASE (fluticasone propionate) Nasal Spray at regular intervals for optimal effect.
Adults: The recommended starting dosage in adults is 2 sprays (50 mcg of fluticasone propionate each) in each nostril once daily (total daily dose, 200 mcg). The same dosage divided into 100 mcg given twice daily (e.g., 8 a.m. and 8 p.m.) is also effective. After the first few days, patients may be able to reduce their dosage to 100 mcg (1 spray in each nostril) once daily for maintenance therapy. Some patients (12 years of age and older) with seasonal allergic rhinitis may find as-needed use of 200 mcg once daily effective for symptom control (see Clinical Trials). Greater symptom control may be achieved with scheduled regular use.
Adolescents and Children (4 Years of Age and Older): Patients should be started with 100 mcg (1 spray in each nostril once daily). Patients not adequately responding to 100 mcg may use 200 mcg (2 sprays in each nostril). Once adequate control is achieved, the dosage should be decreased to 100 mcg (1 spray in each nostril) daily.
The maximum total daily dosage should not exceed 2 sprays in each nostril (200 mcg/day). (See Individualization of Dosage and Clinical Trials sections.)
FLONASE (fluticasone propionate) Nasal Spray is not recommended for children under 4 years of age.
Directions for Use: Illustrated patient's instructions for proper use accompany each package of FLONASE (fluticasone propionate) Nasal Spray.
FLONASE (fluticasone propionate) Nasal Spray 50 mcg is supplied in an amber glass bottle fitted with a white metering atomizing pump, white nasal adapter, and green dust cover in a box of 1 (NDC 0173-0453-01) with patient's instructions for use. Each bottle contains a net fill weight of 16 g and will provide 120 actuations. Each actuation delivers 50 mcg of fluticasone propionate in 100 mg of formulation through the nasal adapter. The correct amount of medication in each spray cannot be assured after 120 sprays even though the bottle is not completely empty. The bottle should be discarded when the labeled number of actuations has been used.
Store between 4° and 30°C (39° and 86°F).
GlaxoSmithKline., Research Triangle Park, NC 27709. FDA rev date: 3/26/2004
Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.
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