Florinef (Fludrocortisone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 7, 2012

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

FLORINEF® ACETATE
(fludrocortisone acetate) Tablets USP

DRUG DESCRIPTION

Florinef Acetate (Fludrocortisone Acetate Tablets USP) contains fludrocortisone acetate, a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity; it is used only for its mineralocorticoid effects. The chemical name for fludrocortisone acetate is 9-fluoro-11β,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; its graphic formula is:

Florinef Acetate (Fludrocortisone Acetate) structural formula illustration

Florinef (fludrocortisone) Acetate is available for oral administration as scored tablets providing 0.1 mg fludrocortisone acetate per tablet. Inactive ingredients: calcium phosphate, corn starch, lactose, magnesium stearate, sodium benzoate, and talc.

What are the possible side effects of fludrocortisone (Florinef Acetate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

problems with your vision;
swelling, rapid weight gain, feeling short of breath;
severe depression, unusual thoughts or behavior, seizure (convulsions);
bloody or tarry stools, coughing up blood;
pancreatitis (severe pain in your upper...

Read All Potential Side Effects and See Pictures of Florinef »

What are the precautions when taking fludrocortisone (Florinef)?

Before taking fludrocortisone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: fungal infection in your blood (e.g., candidiasis, valley fever).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye problems (e.g., cataracts, glaucoma, infection of the eye), heart problems (e.g., congestive heart failure), high blood...

Read All Potential Precautions of Florinef »

Last reviewed on RxList: 12/13/2007
This monograph has been modified to include the generic and brand name in many instances.