"The U.S. Food and Drug Administration will complete its phase-out of all inhaler medical products containing chlorofluorocarbons (CFCs) by Dec. 31, 2013. This effort is to comply with an international treaty to protect the ozone layer by phasing "...
FLOVENT® 44 mcg (fluticasone propionate, 44 mcg) Inhalation Aerosol
FLOVENT® 110 mcg
(fluticasone propionate, 110 mcg) Inhalation Aerosol
FLOVENT® 220 mcg
(fluticasone propionate, 220 mcg) Inhalation Aerosol
For Oral Inhalation Only
The active component of FLOVENT (fluticasone propionate) 44 mcg Inhalation Aerosol, FLOVENT (fluticasone propionate) 110 mcg Inhalation Aerosol, and FLOVENT 220 mcg Inhalation Aerosol is fluticasone propionate, a glucocorticoid having the chemical name S-(fluoromethyl)6a,9-difluoro-11b,17-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioate, 17-propionate and the following chemical structure:
Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.
FLOVENT (fluticasone propionate) 44 mcg Inhalation Aerosol, FLOVENT (fluticasone propionate) 110 mcg Inhalation Aerosol, and FLOVENT (fluticasone propionate) 220 mcg Inhalation Aerosol are pressurized, metered-dose aerosol units intended for oral inhalation only. Each unit contains a microcrystalline suspension of fluticasone propionate (micronized) in a mixture of 2 chlorofluorocarbon propellants (trichlorofluoromethane and dichlorodifluoromethane) with soya lecithin. Each actuation of the inhaler delivers 50, 125, or 250 mcg of fluticasone propionate from the valve and 44, 110, or 220 mcg, respectively, of fluticasone propionate from the actuator.
Last reviewed on RxList: 12/30/2004
This monograph has been modified to include the generic and brand name in many instances.
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