Flumadine (Rimantadine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 8, 2012

Flumadine

Bird Flu »

Bird flu facts

Bird flu refers to strains of influenza that primarily affect wild and domesticated birds.
Bird flu is also known as avian flu or avian influenza.
Although bird flu is contagious and spreads easily among birds, it is uncommon for it to be transmitted to humans.
In the late 1990s, a new strain of bird flu arose which was unusually severe ("highly pathogenic"), resulting in the deaths of hundreds of millions of birds, including poultry.
Control efforts, including culling infected flocks and vaccinating healthy birds, have limited the spread of highly pathogenic bird flu.
In 2011, a mutated strain of highly pathogenic bird flu appeared, which is concerning because the existing poultry vaccines are not very effective against the new strain.
Human infection with the highly pathogenic strain of bird flu is uncommon, with fewer than 600 cases reported since 1997.
Huma...

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Flumadine

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Flumadine®
(rimantadine hydrochloride) Tablets

DRUG DESCRIPTION

Flumadine® (rimantadine hydrochloride) is a synthetic antiviral drug available as a 100 mg film-coated tablet. Each film-coated tablet contains 100 mg of rimantadine hydrochloride plus hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, FD&C Yellow No. 6 Lake and FD&C Yellow No. 6. The film coat contains hypromellose and polyethylene glycol.

Rimantadine hydrochloride is a white to off-white crystalline powder which is freely soluble in water (50 mg/mL at 20°C). Chemically, rimantadine hydrochloride is alpha-methyltricyclo-[3.3.1.1/3.7]decane-1-methanamine hydrochloride, with an empirical formula of C₁₂H₂₁N•HCI, a molecular weight of 215.77 and the following structural formula:

Flumadine®
(rimantadine hydrochloride) Structural Formula Illustration

What are the possible side effects of rimantadine (Flumadine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using rimantadine and call your doctor at once if you have a seizure (black-out or convulsions).

Less serious side effects may include:

nausea, vomiting, diarrhea, loss of appetite, stomach pain;
dry mouth;
sleep problems (insomnia);
dizziness;
headache; or
anxiety, trouble...

Read All Potential Side Effects and See Pictures of Flumadine »

What are the precautions when taking rimantadine (Flumadine)?

Before taking rimantadine, tell your doctor or pharmacist if you are allergic to it; or to amantadine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, seizures.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for dizziness,...

Read All Potential Precautions of Flumadine »

Last reviewed on RxList: 4/26/2010
This monograph has been modified to include the generic and brand name in many instances.