"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
DOSAGE AND ADMINISTRATION
The patient should be instructed to apply sufficient medication to cover the entire face or other affected areas.
Apply medication twice daily with fingertips and wash hands afterwards. A treatment period of 2-6 weeks is usually required.
Increasing the frequency of application and a longer period of administration with FLUOROPLEX® (fluorouracil topical cream) Cream may be required on areas other than the head and neck.
When FLUOROPLEX® (fluorouracil topical cream) Cream is applied to keratotic skin, a response occurs with the following sequence: erythema, usually followed by scaling, tenderness, erosion, ulceration, necrosis and re-epithelization. When the inflammatory reaction reaches the erosion, ulceration and necrosis stages, the use of the drug should be terminated. Responses may sometimes occur in areas which appear clinically normal. These may be sites of subclinical actinic (solar) keratosis which the medication is affecting.
NOTE: Avoid freezing. Store at 15° - 30°C (59° - 86°F) in tight containers.
Revised November 2004. Manufactured for: Allergan, Inc. Irvine, California 92612, U.S.A. By Contract Pharmaceuticals Limited Mississauga Ontario, Canada L5N 6L6This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 5/6/2009
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