Recommended Topic Related To:

Fluothane

"Below is a list of the most popular prescription drugs dispensed in 2011 with links to drug monographs. The list may include the medication brand name and generic name.

Note: This information pertains to U.S. prescriptions only./"...

Fluothane

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

SIDE EFFECTS

As with other agents of this type, halothane anaesthesia has been shown to trigger a skeletal muscle hypermetabolic state leading to high oxygen demand and the clinical syndrome known as malignant hyperthermia (MH). The syndrome includes non specific features such as hypercapnia, muscle rigidity, tachycardia, tachypnoea, cyanosis, arrhythmias and unstable blood pressure. An increase in overall metabolism may be reflected in an elevated temperature. Treatment includes discontinuation of triggering agents, administration of intravenous dantrolene sodium and application of supportive therapy.

Cardiac arrhythmias, in particular ventricular arrthymias, have been reported as being very common during FLUOTHANE (halothane) use. Typically these are without clinical consequences. Bradycardia and/or hypotension may occur during FLUOTHANE (halothane) anaesthesia. Hypotension may occur particularly during induction.

Shivering may be observed during recovery from anaesthesia, especially if the patient is in cool surroundings.

Post-operative nausea and vomiting may occur after FLUOTHANE anaesthesia.

Anaesthesia with halothane may be followed by abnormalities of liver function or more rarely liver damage (see Contraindications).

Read the Fluothane (halothane) Side Effects Center for a complete guide to possible side effects

DRUG INTERACTIONS

FLUOTHANE (halothane) augments the action of non-depolarising muscle relaxants and the muscle relaxant effects of aminoglycosides.

FLUOTHANE (halothane) may augment the hypotension caused by the ganglionic-blocking effect of tubocurarine.

Caution should be exercised during the administration of adrenaline to patients anaesthetised with FLUOTHANE (halothane) as arrhythmias may be precipitated. For this reason the dose of adrenaline should be restricted and an antiarrhythmic agent administered as appropriate. Caution should also be applied for other sympathomimetics, and for aminophylline and theophylline and tricyclic antidepressants, which may also precipitate arrhythmias.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

A A A

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations