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Fluress® (Fluorescein Sodium and Benoxinate Hydrochloride Ophthalmic Solution USP) is a sterile ophthalmic solution combining a disclosing agent with an anesthetic agent.

Fluorescein sodium is a disclosing agent with molecular formula C₂₀H₁₀Na₂O₅, molecular weight 376.28, and chemical structure:

Chemical Name:

Spiro[isobenzofuran-1(3H), 9'-[9H]xanthene]-3-one, 3'6'-dihydroxy, Disodium salt

Benoxinate Hydrochloride is an anesthetic agent with molecular formula C₁₇H₂₈N₂O₃•HCl, molecular weight 344.88, and chemical structure:

Chemical Name: Benzoic acid, 4-amino-3-butoxyl-,2-(diethylamino) ethyl ester, monohydrochloride

Each mL contains:

Active: Benoxinate Hydrochloride 4 mg (0.4%), Fluorescein Sodium 2.5 mg (0.25%).

Preservative: Chlorobutanol 10 mg (1%).

Inactive: Povidone, Boric Acid, Sodium Hydroxide and/or Hydrochloric Acid (to adjust pH), Purified Water USP.

Last reviewed on RxList: 2/25/2009
This monograph has been modified to include the generic and brand name in many instances.