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Folotyn

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Folotyn

Folotyn

Folotyn Patient Information Including Side Effects

Brand Names: Folotyn

Generic Name: pralatrexate (Pronunciation: PRAL a TREX ate)

What is pralatrexate (Folotyn)?

Pralatrexate is a cancer medication.

Pralatrexate is used to treat T-cell lymphoma that has spread throughout the body.

Pralatrexate is given for relapsed T-cell lymphoma, or after other medications have been tried without successful treatment.

Pralatrexate may also be used for purposes not listed in this medication guide.

What are the possible side effects of pralatrexate (Folotyn)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • taste loss, mouth pain, redness or ulcers, or white-yellow mouth sores;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • fever, chills, body aches, flu symptoms, rapid heart rate, rapid and shallow breathing, fainting;
  • pale skin, feeling light-headed or short of breath, trouble concentrating;
  • weakness, decreased sweating, hot or dry skin; or
  • confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.

Less serious side effects may include:

  • nausea, vomiting, loss of appetite;
  • diarrhea, constipation;
  • tired feeling;
  • cough;
  • swelling; or
  • mild rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Folotyn (pralatrexate solution for intravenous injection) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about pralatrexate (Folotyn)?

Before you receive pralatrexate, tell your doctor if you have kidney disease.

You should not breast-feed a baby while you are being treated with pralatrexate.

You may be required to take oral folic acid supplements and receive vitamin B12 injections to help prevent some of the side effects of pralatrexate. Follow your doctor's medication instructions very closely.

To make sure this medication is not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.

Call your doctor at once if you have a serious side effect such as fever, flu symptoms, mouth ulcers, easy bruising or bleeding, pale skin, rapid heart rate, trouble breathing, weakness, or feeling like you might pass out.

Side Effects Centers
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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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