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Forane Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Forane (isoflurane) is used to induce and maintain general anesthesia. It is a general inhalation anesthetic drug. This medication is available in generic form. Common side effects include slow or shallow breathing, low blood pressure, or abnormally fast or slow heart rate. Post-operatively, side effects include shivering, nausea, vomiting, and abdominal distention or gas.
To induce surgical anesthesia, the dose of Forane used is inspired concentrations of 1.5 to 3.0%. Surgical levels of anesthesia may be sustained with a 1.0 to 2.5% concentration when nitrous oxide is used at the same time. An additional 0.5 to 1.0% may be required when given using oxygen alone. Forane may interact with muscle relaxants. Tell your doctor all medications and supplements you use. During pregnancy, Forane should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Forane (isoflurane) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Forane FDA Prescribing Information: Side Effects
Adverse reactions encountered in the administration of FORANE (isoflurane, USP) are in general dose dependent extensions of pharmacophysiologic effects and include respiratory depression, hypotension and arrhythmias.
Shivering, nausea, vomiting and ileus have been observed in the postoperative period.
As with all other general anesthetics, transient elevations in white blood count have been observed even in the absence of surgical stress. See WARNINGS for information regarding malignant hyperthermia and elevated carboxyhemoglobin levels.
During marketing, there have been rare reports of mild, moderate and severe (some fatal) postoperative hepatic dysfunction and hepatitis.
FORANE (isoflurane, USP) has also been associated with perioperative hyperkalemia (see WARNINGS).
The following adverse events have been identified during post-approval use of FORANE (isoflurane, USP). Due to the spontaneous nature of these reports, the actual incidence and relationship of FORANE (isoflurane, USP) to these events cannot be established with certainty.
Cardiac Disorders: Cardiac arrest
Hepatobiliary Disorders: Hepatic necrosis, Hepatic failure .
Read the entire FDA prescribing information for Forane (Isoflurane) »
Additional Forane Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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