Fosamax Plus D
"Feb. 22, 2011 -- There is new evidence that long-term use of the most widely prescribed bone loss drugs may increase the risk for uncommon but serious femur (thigh bone) fractures.
In an analysis involving more than 200,000 postmenopa"...
Fosamax Plus D
Fosamax Plus D
Fosamax Plus D Patient Information Including Side Effects
Brand Names: Fosamax Plus D
Generic Name: alendronate and cholecalciferol (Pronunciation: a LEN dro nate and KOL e cal SIF er ol)
- What is alendronate and cholecalciferol (Fosamax Plus D)?
- What are the possible side effects of alendronate and cholecalciferol (Fosamax Plus D)?
- What is the most important information I should know about alendronate and cholecalciferol (Fosamax Plus D)?
- What should I discuss with my healthcare provider before taking alendronate and cholecalciferol (Fosamax Plus D)?
- How should I take alendronate and cholecalciferol (Fosamax Plus D)?
- What happens if I miss a dose (Fosamax Plus D)?
- What happens if I overdose (Fosamax Plus D)?
- What should I avoid while taking alendronate and cholecalciferol (Fosamax Plus D)?
- What other drugs will affect alendronate and cholecalciferol (Fosamax Plus D)?
- Where can I get more information?
What is alendronate and cholecalciferol (Fosamax Plus D)?
Alendronate is in the group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures.
Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.
Alendronate and cholecalciferol is used to treat and prevent osteoporosis.
Alendronate and cholecalciferol may also be used for purposes not listed in this medication guide.
Fosamax Plus D
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What are the possible side effects of alendronate and cholecalciferol (Fosamax Plus D)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using alendronate and cholecalciferol and call your doctor at once if you have a serious side effect such as:
- chest pain;
- difficulty or pain when swallowing;
- pain or burning under the ribs or in the back;
- new or worsening heartburn;
- severe joint, bone, or muscle pain;
- new or unusual pain in your thigh or hip; or
- jaw pain, numbness, or swelling.
Less serious side effects may include:
- mild heartburn, nausea, or stomach upset;
- diarrhea, gas, or constipation;
- mild joint or back pain; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Fosamax Plus D (alendronate sodium and cholecalciferol) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about alendronate and cholecalciferol (Fosamax Plus D)?
Do not take an alendronate and cholecalciferol tablet if you cannot sit upright or stand for at least 30 minutes. This medicine can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking the medicine.
Take the alendronate and cholecalciferol tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.
Take each dose with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an alendronate and cholecalciferol tablet.
For at least the first 30 minutes after taking this medicine, do not lie down or recline; do not eat or drink anything other than plain water; and do not take any other medicines including vitamins, calcium, or antacids.
Some people using medicines similar to alendronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate and cholecalciferol. You may need to stop using the medicine for a short time.
Talk with your doctor about the risks and benefits of using this medication.
Additional Fosamax Plus D Information
- Fosamax Plus D Drug Interactions Center: alendronate-vitamin d3 oral
- Fosamax Plus D Side Effects Center
- Fosamax Plus D Overview including Precautions
- Fosamax Plus D FDA Approved Prescribing Information including Dosage
Fosamax Plus D - User Reviews
Fosamax Plus D User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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