"The US Food and Drug Administration (FDA) has approved atazanavir and cobicistat (Evotaz, Bristol-Myers Squibb) for treatment of adults with human immunodeficiency virus (HIV-1) infection.
Atazanavir/cobicistat is a fixed-dos"...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
FOSCARNET SODIUM - INJECTION
COMMON BRAND NAME(S): Foscavir
WARNING: This medication is used only for cytomegalovirus (CMV) eye infections and acyclovir-resistant herpes infections.
Decreased kidney function is a serious side effect caused by this medication. Tell your doctor immediately if you experience a change in the amount of urine. Your doctor may need to adjust your dose.
This medication has caused seizures in some people due to changes in blood chemistry (minerals and electrolytes). Your doctor may prescribe additional minerals and/or electrolytes to prevent seizures.
It is important that you receive appropriate amounts of fluid (hydration) while using this medication.
Your doctor will monitor your blood and kidneys while you are using this medication.
USES: This medication is used to control cytomegalovirus (CMV) eye infections (CMV retinitis) in persons with AIDS. This medication is an antiviral that works by stopping the growth of viruses. Controlling CMV retinitis can help decrease the risk of blindness from the infection. Foscarnet is sometimes combined with another antiviral drug, ganciclovir, when the CMV infection does not respond to either drug used alone for treatment.
This medication is also used to treat herpes infections (HSV) that do not respond to treatment with acyclovir (acyclovir-resistant).
This medication is not a cure for CMV or HSV diseases.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used to help prevent CMV disease in patients receiving cancer treatment (such as chemotherapy).
HOW TO USE: This medication is given by injection into a vein by a health care professional in a hospital or clinic setting. If you are using this medication at home, learn all preparation and usage instruction from your health care professional. If you have any questions about using this medication properly, consult your doctor or pharmacist.
Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. It is usually infused slowly over 1 to 2 hours using an infusion pump. Infusing this medication too quickly can result in serious side effects. Do not mix with any other medications. When starting this medication, you will receive 2 to 3 doses per day for the first 2 to 3 weeks of treatment. This starting period is called "induction." Once induction is completed, you will then be given this medication usually once a day for the remainder of treatment. Dosage is based on your weight, kidney function, medical condition, and response to treatment.
To prevent kidney damage, it is important to drink plenty of fluids while using this medication. Fluids may be given by vein to make sure you get enough.
Antivirals work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals.
It is very important to continue using this medication exactly as prescribed by your doctor. Stopping treatment too soon may result in ineffective treatment.
Do not use more of this drug or infuse it more often or faster than prescribed by your doctor. Your condition will not improve faster, and you may experience side effects.
If skin contact occurs, flush with plenty of water. If irritation occurs, contact your doctor immediately.
Learn how to store and discard needles, medical supplies, and any unused medication safely. Consult your pharmacist. Never reuse needles or syringes.
Additional Foscavir Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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