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In this Article

• What is dalteparin (Fragmin)?
• What are the possible side effects of dalteparin (Fragmin)?
• What is the most important information I should know about dalteparin (Fragmin)?
• What should I discuss with my healthcare provider before receiving dalteparin (Fragmin)?
• How should I use dalteparin (Fragmin)?
• What happens if I miss a dose (Fragmin)?
• What happens if I overdose (Fragmin)?
• What should I avoid while using dalteparin (Fragmin)?
• What other drugs will affect dalteparin (Fragmin)?
• Where can I get more information?

What should I discuss with my healthcare provider before receiving dalteparin (Fragmin)?

You should not receive this medication if you are allergic to dalteparin, or if you have:

• uncontrolled bleeding;
• a severe lack of platelets in your blood;
• if you are having surgery with spinal or epidural anesthesia; or
• if you are allergic to pork products.

Before using dalteparin, tell your doctor if you are allergic to any drugs, or if you have:

• eye problems caused by diabetes or high blood pressure,
• an infection of the lining of your heart (also called bacterial endocarditis);
• uncontrolled high blood pressure;
• a bleeding or blood clotting disorder, such as hemophilia;
• stomach or intestinal bleeding or disorder;
• kidney disease;
• liver disease; or
• if you have ever had a blood cell problem after receiving heparin.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use dalteparin.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether dalteparin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How should I use dalteparin (Fragmin)?

Dalteparin is given as an injection under the skin of your stomach, upper thigh, or buttocks. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to inject your medicine at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

You should be sitting or lying down while receiving a dalteparin injection.

Use a different place on your body each time you give yourself an injection. Your doctor will show you the places on your body where you can safely inject dalteparin. Do not inject this medicine into the same place two times in a row.

If you are using a single-dose prefilled syringe, follow the injection instructions closely. Single-dose syringes come in two different types and the directions for use are not the same for each type.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled appointments..

If you need to have any type of surgery, tell the surgeon ahead of time that you are using dalteparin. You may need to stop using the medicine for a short time.

Store dalteparin vials (bottles) at room temperature away from moisture and heat. Once you have used a vial for the first time, the medicine will keep at room temperature for up to 2 weeks. Throw away the vial after 2 weeks have passed since you first used the vial, even if there is still medicine left in it.

Do not use any medication that is discolored or that has particles in it. Call your doctor for a new prescription.