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Brand Names: Fragmin

Generic Name: dalteparin (Pronunciation: DAL te PAR in)

• What is dalteparin (Fragmin)?
• What are the possible side effects of dalteparin (Fragmin)?
• What is the most important information I should know about dalteparin (Fragmin)?
• What should I discuss with my healthcare provider before receiving dalteparin (Fragmin)?
• How should I use dalteparin (Fragmin)?
• What happens if I miss a dose (Fragmin)?
• What happens if I overdose (Fragmin)?
• What should I avoid while using dalteparin (Fragmin)?
• What other drugs will affect dalteparin (Fragmin)?
• Where can I get more information?

What is dalteparin (Fragmin)?

Dalteparin is an anticoagulant (blood thinner) that prevents the formation of blood clots.

Dalteparin is used to treat or prevent blood clots in the veins, arteries, or lung that can be caused by cancer or certain heart conditions. Dalteparin is also used before surgery to reduce the risk of blood clots.

Dalteparin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of dalteparin (Fragmin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; itching or burning skin; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• easy bruising or bleeding, unusual weakness;
• any bleeding that will not stop;
• blood in your urine or stools, black or tarry stools;
• coughing up blood or vomit that looks like coffee grounds;
• bruising, bleeding, swelling, or skin changes where the medicine was injected;
• nausea, sweating, feeling light-headed, fainting;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• pain or swelling in one or both legs; or
• trouble breathing.

Less serious side effects include mild pain, redness, or warmth where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dalteparin (Fragmin)?

You should not receive this medication if you are allergic to dalteparin or pork products, or if you have uncontrolled bleeding, a severe lack of platelets in your blood, or if you are having surgery with spinal or epidural anesthesia.

Before you receive dalteparin, tell your doctor if you have eye problems caused by diabetes or high blood pressure, an infection of your heart, uncontrolled high blood pressure, a bleeding or blood clotting disorder, stomach or intestinal bleeding, liver disease, or if you have ever had a blood cell problem caused by heparin.

Avoid taking aspirin while you are receiving dalteparin, unless your doctor recommends it as part of your treatment. Aspirin can increase your risk of bleeding.

Tell your doctor about all the prescription and over-the-counter medications you use, especially blood thinners, aspirin, NSAIDs (such as Advil, Motrin Aleve, Orudis), or other medications used to treat or prevent blood clots. Do not start using a new medication without telling your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using dalteparin. You may need to stop using the medicine for a short time.