In this Article

• What is amphotericin B (Fungizone)?
• What are the possible side effects of amphotericin B (Fungizone)?
• What is the most important information I should know about amphotericin B (Fungizone)?
• What should I discuss with my health care provider before I receive amphotericin B (Fungizone)?
• How is amphotericin B given (Fungizone)?
• What happens if I miss a dose (Fungizone)?
• What happens if I overdose (Fungizone)?
• What should I avoid while receiving amphotericin B (Fungizone)?
• What other drugs will affect amphotericin B (Fungizone)?
• Where can I get more information?

What happens if I miss a dose (Fungizone)?

Since amphotericin B is usually given while you are in the hospital, it is not likely you will miss a dose of this medication.

If you are receiving amphotericin B in an outpatient clinic, call your doctor if you will miss an appointment for your amphotericin B injection.

What happens if I overdose (Fungizone)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include slow heart rate, and shallow breathing that slows or stops.

What should I avoid while receiving amphotericin B (Fungizone)?

Amphotericin B may lower the blood cells that help your body fight other infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

What other drugs will affect amphotericin B (Fungizone)?

Before receiving amphotericin B, tell your doctor if you are using any of the following drugs:

• flucytosine (Ancobon);
• digoxin (digitalis, Lanoxin, Lanoxicaps);
• pentamidine (Nebupent, Pentam);
• tacrolimus (Prograf);
• muscle relaxers;
• steroids (prednisone and others);
• antifungal antibiotics such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), ketoconazole (Nizoral), or itraconazole (Sporanox);
• antibiotics such as capreomycin (Capastat), rifampin (Rifadin, Rimactane, Rifater), vancomycin (Vancocin, Vancoled);
• antiviral medicines such as acyclovir (Zovirax), adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or
• cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), plicamycin (Mithracin), streptozocin (Zanosar), or tretinoin (Vesanoid).

This list is not complete and there may be other drugs that can interact with amphotericin B. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about amphotericin B.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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