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Fuzeon

Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.

Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.

CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...

Fuzeon

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Fuzeon Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Fuzeon Prescribing Information: Indications & Dosage

FUZEON® (enfuvirtide) Structural Formula Illustration

FUZEON® in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection in treatment-experienced patients with evidence of HIV-1 replication despite ongoing antiretroviral therapy.

This indication is based on results from two controlled studies of 48 weeks duration. Subjects enrolled were treatment-experienced adults; many had advanced disease. There are no studies of FUZEON in antiretroviral naive subjects.

Read the complete drug monograph for Fuzeon »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Fuzeon Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; fever, chills; nausea, vomiting; difficulty breathing; feeling light-headed or fainting; swelling of your face, lips, tongue, or throat.

Stop using enfuvirtide and call your doctor at once if you have any of these serious side effects:

  • cough with fever, chest congestion, and shortness of breath;
  • signs of a new infection, such as fever or chills, cough, or flu symptoms.
  • nerve pain lasting for several weeks or months; or
  • severe or ...

Read the complete patient information for Fuzeon »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Fuzeon Consumer Information: Uses

This medication is used in combination with other anti-HIV drugs to treat HIV (Human Immunodeficiency Virus) infection.

It works by blocking the HIV virus' ability to infect healthy immune cells (CD4 cells).

This medication does not cure HIV. Patients treated with this medication may continue to acquire "opportunistic" infections associated with HIV. This product also does not prevent the spread of HIV to others through sexual contact, blood, or sharing of needles.

HOW TO USE: Inject this medication under the skin (subcutaneously) usually twic...

Read the complete consumer information for Fuzeon »

What is Fuzeon Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Fuzeon - User Reviews

Fuzeon User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Fuzeon sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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