DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: a certain drug for stopping smoking (bupropion), certain anti-seizure drugs (e.g., phenytoin, carbamazepine, phenobarbital, primidone), certain recreational/street drugs such as methamphetamine ("speed") or MDMA ("ecstasy").

Certain medications increase your chances of having a seizure and may make it appear that tiagabine and your other anti-seizure medications are not working. Tell your doctor or pharmacist if you are taking other drugs which might increase seizure risk when combined with tiagabine such as bupropion, isoniazid, antipsychotic medications (e.g., phenothiazines such as chlorpromazine), stimulants (e.g., methylphenidate, dextroamphetamines) or alcohol.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-anxiety drugs (e.g., diazepam), anti-seizure drugs (e.g., gabapentin, valproic acid), medicine for sleep (e.g., zolpidem, temazepam), narcotic pain relievers (e.g., codeine, fentanyl), tranquilizers, or certain antidepressants (e.g., tricyclics such as imipramine or amitriptyline).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include uncontrolled seizures (status epilepticus), slow/shallow breathing.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (e.g., blood levels of tiagabine, EEG tests) may be performed to monitor your response to therapy and check for side effects.

Report any increase in the number of seizures or changes in seizure symptoms.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. If you miss taking this medication for several days, contact your doctor for instructions.

STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

Information last revised October 2010. Copyright(c) 2010 First Databank, Inc.