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Brand Names: Antagon, Ganirelix Acetate

Generic Name: ganirelix (Pronunciation: GA ni REL ix)

• What is ganirelix (Ganirelix Acetate Injection)?
• What are the possible side effects of ganirelix (Ganirelix Acetate Injection)?
• What is the most important information I should know about ganirelix (Ganirelix Acetate Injection)?
• What should I discuss with my healthcare provider before using ganirelix (Ganirelix Acetate Injection)?
• How should I use ganirelix (Ganirelix Acetate Injection)?
• What happens if I miss a dose (Ganirelix Acetate Injection)?
• What happens if I overdose (Ganirelix Acetate Injection)?
• What should I avoid while using ganirelix (Ganirelix Acetate Injection)?
• What other drugs will affect ganirelix (Ganirelix Acetate Injection)?
• Where can I get more information?

What is ganirelix (Ganirelix Acetate Injection)?

Ganirelix is a man-made form of a protein that reduces the amount of certain hormones in the body, including estrogen.

Ganirelix is used along with other medications to regulate hormones during treatment for infertility in women.

Ganirelix may also be used for other purposes not listed in this medication guide.

What are the possible side effects of ganirelix (Ganirelix Acetate Injection)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any of the following symptoms of OHSS:

• severe pelvic pain;
• swelling of the hands or legs;
• stomach pain and swelling;
• shortness of breath;
• weight gain;
• diarrhea;
• nausea or vomiting; or
• urinating less than normal.

Less serious side effects may include:

• pelvic pain (similar to menstrual cramps);
• mild nausea or stomach pain;
• headache;
• vaginal bleeding; or
• pain, redness, or irritation at the injection site.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ganirelix (Ganirelix Acetate Injection)?

You should not use this medication if you are allergic to ganirelix or similar medications such as leuprolide (Lupron, Eligard), goserelin (Zoladex), or nafarelin (Synarel).

Before using ganirelix, tell your doctor if you are allergic to latex rubber.

Do not use ganirelix if you are already pregnant. Your doctor may give you a pregnancy test to make sure you are not pregnant before you receive ganirelix.

Do not use this medication without telling your doctor if you are breast-feeding a baby.

During your treatment with ganirelix, your blood may need to be tested often. Do not miss any follow-up visits to your doctor. You must remain under the care of your doctor while using ganirelix.

Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any of the following symptoms of OHSS: severe pelvic or stomach pain, swelling or rapid weight gain, shortness of breath, diarrhea, nausea, vomiting, or urinating less than usual.