Gelnique (Oxybutynin Chloride 10 % Gel) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Gelnique

Urinary Incontinence in Women »

Urinary incontinence (UI) in women facts

*Urinary incontinence (UI) in men facts Medically Edited by: Melissa Conrad Stöppler, MD

The definition of urinary incontinence in women is the unintentional loss of urine.
Urinary incontinence occurs more often in women than in men. Pregnancy, childbirth, and menopause may contribute to urinary incontinence in women.
Weak bladder muscles, overactive bladder muscles, and nerve damage may also cause urinary incontinence in women.
Urinary incontinence in women is common and treatable.
There are different types of urinary incontinence in women, including stress incontinence, urge incontinence, overactive bladder, functional incontinence, overflow incontinence, mixed incontinence, and transient incontinence.
Diagnosis of urinary incontinence in women may involve a physical exam, an ultrasound, urodynamic testing, and tests including cystoscopy, urinalysis, and a bl...

Read the Urinary Incontinence in Women article »

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Gelnique

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GELNIQUE
(oxybutynin chloride) 10% Gel

DRUG DESCRIPTION

Oxybutynin is an antispasmodic, antimuscarinic agent. GELNIQUE (oxybutynin chloride) is a clear and colorless hydro alcoholic gel containing 100 mg oxybutynin chloride per gram of gel. GELNIQUE (oxybutynin chloride 10 % gel) is available in a 1 gram (1.14 mL) unit dose that contains 100 mg oxybutynin chloride. Oxybutynin is delivered as a racemate of R- and S-isomers. Chemically, oxybutynin chloride is d, 1 (racemic) 4-(Diethylamino)-2-butynyl (±)-a-phenylcyclohexaneglycolatehydrochloride.

The empirical formula of oxybutynin is C₂₂H₃₁NO₃·HCl. Its structural formula is:

GELNIQUE</b><br />
(oxybutynin chloride) Structural Formula Illustration

Oxybutynin chloride is a white powder with a molecular weight of 393.95.

Inactive ingredients in GELNIQUE (oxybutynin chloride 10 % gel) are alcohol, USP; glycerin, USP; hydroxypropyl cellulose, NF; sodium hydroxide, NF; and purified water, USP.

What are the possible side effects of oxybutynin topical (Gelnique)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using oxybutynin topical and call your doctor at once if you have any of these serious side effects:

fever with hot, dry skin;
uneven heart rate;
pain, burning, or other difficulty when urinating; or
severe itching, redness, pain, rash, or other irritation where the medication was applied.

Less serious...

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What are the precautions when taking oxybutynin chloride 10 % gel (Gelnique)?

Before taking cyclosporine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: history of chickenpox/shingles, uncontrolled high blood pressure, cancer, skin lesions of unknown cause, current use of radiation therapy (including phototherapy with PUVA or UVB), kidney problems (for arthritis or psoriasis patients only).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver...

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Last reviewed on RxList: 3/28/2011
This monograph has been modified to include the generic and brand name in many instances.