"The U.S. Food and Drug Administration today approved Zejula (niraparib) for the maintenance treatment (intended to delay cancer growth) of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, whose tumors"...
Myelosuppression, paresthesias, and severe rash were the principal toxicities seen when a single dose as high as 5700 mg/m² was administered by intravenous infusion over 30 minutes every 2 weeks to several patients in a doseescalation study.
Gemzar is contraindicated in patients with a known hypersensitivity to gemcitabine.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 5/23/2016
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