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Gilenya

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Gilenya

Gilenya

OVERDOSE

GILENYA can induce bradycardia as well as AV conduction blocks (including complete AV block). The decline in heart rate usually starts within 1 hour of the first dose and is maximal within 6 hours in most patients [see WARNINGS AND PRECAUTIONS]. In case of GILENYA overdosage, observe patients overnight with continuous ECG monitoring in a medical facility, and obtain regular measurements of blood pressure [see DOSAGE AND ADMINISTRATION].

Neither dialysis nor plasma exchange results in removal of fingolimod from the body.

CONTRAINDICATIONS

Patients who in the last 6 months experienced myocardial infarction, unstable angina, stroke, TIA, decompensated heart failure requiring hospitalization or Class III/IV heart failure

History or presence of Mobitz Type II second-degree or third-degree atrioventricular (AV) block or sick sinus syndrome, unless patient has a functioning pacemaker

Baseline QTc interval ≥ 500 msec

Treatment with Class Ia or Class III anti-arrhythmic drugs

Last reviewed on RxList: 5/20/2014
This monograph has been modified to include the generic and brand name in many instances.

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Gilenya - User Reviews

Gilenya User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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