Gilenya
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Gilenya
OVERDOSE
GILENYA can induce bradycardia as well as AV conduction blocks (including complete AV block). The decline in heart rate usually starts within one hour of the first dose and is maximal within 6 hours in most patients [see WARNINGS AND PRECAUTIONS]. In case of GILENYA overdosage, observe patients overnight with continuous ECG monitoring in a medical facility, and obtain regular measurements of blood pressure [see DOSAGE AND ADMINISTRATION].
Neither dialysis nor plasma exchange results in removal of fingolimod from the body.
CONTRAINDICATIONS
Patients who in the last 6 months experienced myocardial infarction, unstable angina, stroke, TIA, decompensated heart failure requiring hospitalization or Class III/IV heart failure
History or presence of Mobitz Type II second-degree or third-degree atrioventricular (AV) block or sick sinus syndrome, unless patient has a functioning pacemaker
Baseline QTc interval ≥ 500 ms
Treatment with Class Ia or Class III anti-arrhythmic drugs
Last reviewed on RxList: 5/18/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Gilenya Information
Gilenya - User Reviews
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