"The U.S. Food and Drug Administration today approved a new use of Gleevec (imatinib) to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL).
ALL is the most common type of pediatric "...
Gleevec Patient Information including If I Miss a Dose
In this Article
- What is imatinib (Gleevec)?
- What are the possible side effects of imatinib (Gleevec)?
- What is the most important information I should know about imatinib (Gleevec)?
- What should I discuss with my healthcare provider before taking imatinib (Gleevec)?
- How should I take imatinib (Gleevec)?
- What happens if I miss a dose (Gleevec)?
- What happens if I overdose (Gleevec)?
- What should I avoid while taking imatinib (Gleevec)?
- What other drugs will affect imatinib (Gleevec)?
- Where can I get more information?
What happens if I miss a dose (Gleevec)?
Take the missed dose as soon as you remember, making sure you also eat a meal and drink a large glass of water. Skip the missed dose if it is almost time for your next meal. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Gleevec)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose can cause severe muscle cramps.
What should I avoid while taking imatinib (Gleevec)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect imatinib (Gleevec)?
Many drugs can interact with or be affected by imatinib. Below is just a partial list. Tell your doctor if you are using:
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
- digoxin (digitalis, Lanoxin, Lanoxicaps);
- fentanyl (Actiq, Duragesic, Fentora);
- isoniazid (for treating tuberculosis);
- pimozide (Orap);
- sirolimus (Rapamune) or tacrolimus (Prograf);
- St. John's wort;
- theophylline (Elixophyllin, Theo-24, Theochron, Uniphyl);
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), rifapentine (Priftin), or telithromycin (Ketex);
- antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), or miconazole (Oravig);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- a blood thinner such as warfarin (Coumadin, Jantoven);
- cholesterol-lowering medicines such as atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin);
- ergot medicine such as ergotamine (Ergomar, Cafergot) or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray);
- heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
- a heart rhythm medication such as disopyramide (Norpace), procainamide (Procan, Pronestyl), or quinidine (Quin-G);
- HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Norvir, Kaletra);
- medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), divalproex (Depakote), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), primidone (Mysoline), valproic acid (Depakene).
This list is not complete and other drugs may interact with imatinib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about imatinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 9.01. Revision date: 7/14/2011.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Gleevec Information
- Gleevec Drug Interactions Center: imatinib oral
- Gleevec Side Effects Center
- Gleevec Overview including Precautions
- Gleevec FDA Approved Prescribing Information including Dosage
Gleevec - User Reviews
Gleevec User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.