February 7, 2016
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Glucotrol XL

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Glucotrol XL




Overdosage
Contraindications

OVERDOSE

Overdosage of sulfonylureas including glipizide can produce severe hypoglycemia. Mild hypoglycemic symptoms without loss of consciousness or neurologic findings should be treated with oral glucose. Severe hypoglycemic reactions with coma, seizure, or other neurological impairment are medical emergencies requiring immediate treatment. The patient should be treated with glucagon or intravenous glucose. Patients should be closely monitored for a minimum of 24 to 48 hours since hypoglycemia may recur after apparent clinical recovery. Clearance of glipizide from plasma may be prolonged in persons with liver disease. Because of the extensive protein binding of glipizide, dialysis is unlikely to be of benefit.

CONTRAINDICATIONS

Glipizide is contraindicated in patients with:

  • Known hypersensitivity to glipizide or any of the product's ingredients.
  • Hypersensitivity to sulfonamide derivatives.
This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 12/1/2015

Overdosage
Contraindications

Glucotrol XL - User Reviews

Glucotrol XL User Reviews

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