"The US Food and Drug Administration (FDA) has approved a new type 2 diabetes drug that combines the sodium glucose cotransporter 2 (SGLT2) inhibitor empagliflozin with metformin hydrochloride (Synjardy, Boehringer Ingelheim and Eli Lilly"...
Glucovance Patient Information including How Should I Take
In this Article
- What is glyburide and metformin (Glucovance)?
- What are the possible side effects of glyburide and metformin (Glucovance)?
- What is the most important information I should know about glyburide and metformin (Glucovance)?
- What should I discuss with my healthcare provider before taking glyburide and metformin (Glucovance)?
- How should I take glyburide and metformin (Glucovance)?
- What happens if I miss a dose (Glucovance)?
- What happens if I overdose (Glucovance)?
- What should I avoid while taking glyburide and metformin (Glucovance)?
- What other drugs will affect glyburide and metformin (Glucovance)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking glyburide and metformin (Glucovance)?
You should not use this medication if you are allergic to glyburide or metformin, if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
- kidney disease; or
- if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking glyburide and metformin.
Some people develop a life-threatening condition called lactic acidosis while taking metformin. You may be more likely to develop lactic acidosis if you have liver or kidney disease, congestive heart failure, a severe infection, if you are dehydrated, or if you drink large amounts of alcohol. Older adults may also have a higher risk of developing lactic acidosis. Talk with your doctor about your individual risk.
To make sure you can safely take this medication, tell your doctor if you have any of these other conditions:
- an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
- liver disease; or
- heart disease or a history of heart attack or stroke.
- a history of heart attack or stroke.
FDA pregnancy category B. This medicine is not expected to harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking glyburide and metformin.
Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with glyburide and metformin.
How should I take glyburide and metformin (Glucovance)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Take glyburide and metformin with meals. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.
Keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.
Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.
Ask your doctor how to adjust your dose if needed. Do not change your medication dose or schedule without your doctor's advice.
If you need surgery, tell the surgeon ahead of time that you are using glyburide and metformin. You may need to stop using the medicine for a short time.
This medicine is only part of a complete program of treatment that also includes diet, exercise, and weight control.
Store at room temperature away from moisture, heat, and light.
Additional Glucovance Information
- Glucovance Drug Interactions Center: glyburide-metformin oral
- Glucovance Side Effects Center
- Glucovance Overview including Precautions
- Glucovance FDA Approved Prescribing Information including Dosage
Glucovance - User Reviews
Glucovance User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.