"What are oral diabetes medications and how do they work?
Insulin is a hormone produced by cells in the pancreas called beta cells. Insulin helps the body use blood glucose (a type of sugar) for energy. People with type 2 diabetes "...
- Clinician Information:
Glynase PresTab Patient Information including If I Miss a Dose
In this Article
- What is glyburide (Glynase PresTab)?
- What are the possible side effects of glyburide (Glynase PresTab)?
- What is the most important information I should know about glyburide (Glynase PresTab)?
- What should I discuss with my health care provider before taking glyburide (Glynase PresTab)?
- How should I take glyburide (Glynase PresTab)?
- What happens if I miss a dose (Glynase PresTab)?
- What happens if I overdose (Glynase PresTab)?
- What should I avoid while taking glyburide (Glynase PresTab)?
- What other drugs will affect glyburide (Glynase PresTab)?
- Where can I get more information?
What happens if I miss a dose (Glynase PresTab)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Glynase PresTab)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.A glyburide overdose can cause life-threatening hypoglycemia.
Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking glyburide (Glynase PresTab)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
Avoid exposure to sunlight or tanning beds. Glyburide can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
What other drugs will affect glyburide (Glynase PresTab)?
Tell your doctor about all other medications you use, especially:
- a blood thinner such as warfarin (Coumadin, Jantoven);
- cyclosporine (Gengraf, Neoral, Sandimmune);
- disopyramide (Norpace);
- fluconazole (Diflucan), ketoconazole (Nizoral);
- fluoxetine (Prozac);
- rifampin (Rifadin, Rimactane, Rifater);
- an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others; or
- an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), and others.
Using certain medicines can make it harder for you to tell when you have low blood sugar. Tell your doctor if you use any of the following:
- albuterol (Proventil, Ventolin);
- clonidine (Catapres);
- reserpine; or
- beta-blockers such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.
You may be more likely to have hyperglycemia (high blood sugar) if you take glyburide with:
- diuretics (water pills);
- steroids (prednisone and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- heart or blood pressure medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);
- niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- seizure medicines (Dilantin and others); and
- diet pills or medicines to treat asthma, colds or allergies.
You may be more likely to have hypoglycemia (low blood sugar) if you take glyburide with:
- clarithromycin (Biaxin);
- exenatide (Byetta);
- probenecid (Benemid);
- heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, and others);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- sulfa drugs (Bactrim, Gantanol, Septra, and others);
- a monoamine oxidase inhibitor (MAOI); and
- other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).
These lists are not complete and there are many other medicines that can increase or decrease the effects of glyburide on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about glyburide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Glynase PresTab Information
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