November 28, 2015
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"The U.S. Food and Drug Administration today allowed marketing of the Eclipse System for the treatment of fecal incontinence (FI) in adult women.

Fecal incontinence is the inability to control bowel movements and is a common problem, espec"...



Mechanism of Action

The primary mode of action is thought to be through the osmotic effect of polyethylene glycol 3350 which causes water to be retained in the colon and produces a watery stool.


GoLYTELY induces as diarrhea which rapidly cleanses the bowel, usually within four hours.


The pharmacokinetics of PEG3350 following administration of GoLYTELY were not assessed. Available pharmacokinetic information for oral PEG3350 suggests that it is poorly absorbed.

Last reviewed on RxList: 10/4/2013
This monograph has been modified to include the generic and brand name in many instances.

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