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GoLytely Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
GoLytely (polyethylene glycol 3350 and electrolytes) Oral Solution is a combination of a laxative and electrolytes for bowel cleansing prior to colonoscopy and barium enema X-ray examination in adults. GoLytely is available in generic form. Common side effects of GoLytely include nausea, stomach or abdominal fullness, bloating, stomach or abdominal cramps, vomiting, and anal irritation.
GoLytely is a powder that must be reconstituted with water before use. One gallon reconstituted GoLytely solution contains doses of: 227.1 grams of polyethylene glycol (PEG) 3350, 21.5 grams sodium sulfate (anhydrous), 6.36 grams of sodium bicarbonate, 5.53 grams of sodium chloride, and 2.82 grams of potassium chloride. GoLytely may interact with laxatives, and may affect the absorption of other drugs. Tell your doctor all medications and supplements you use. Consult your doctor before taking GoLytely if you are pregnant or breastfeeding.
Our GoLytely (polyethylene glycol 3350 and electrolytes) Oral Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
GoLytely FDA Prescribing Information: Side Effects
The following adverse reactions have been identified during post-approval use of GoLYTELY. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Nausea, abdominal fullness and bloating are the most common adverse reactions (occurred in up to 50% of patients) to administration of GoLYTELY. Abdominal cramps, vomiting and anal irritation occur less frequently. These adverse reactions are transient and usually subside rapidly. Isolated cases of urticaria, rhinorrhea, dermatitis and (rarely) anaphylactic reaction have been reported which may represent allergic reactions.
Published literature contains isolated reports of serious adverse reactions following the administration of PEG-electrolyte solution products in patients over 60 years of age. These adverse events include upper GI bleeding from Mallory-Weiss Tear, esophageal perforation, asystole, sudden dyspnea with pulmonary edema, and “butterfly-like” infiltrates on chest X-ray after vomiting and aspirating PEG.
Read the entire FDA prescribing information for GoLytely (Polyethylene Glycol 3350 and Electrolytes Oral Solution)
Additional GoLytely Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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