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Guaifenex PSE 60

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Guaifenex® PSE 60
(guaifenesin/pseudoephedrine) Extended-release Tablets Expectorant/Nasal Decongestant

DRUG DESCRIPTION

Each bisected, blue Guaifenex® PSE 60 (guaifenesin pseudoephedrine extended-release tablets) capsule shaped extended-release tablet provides 60 mg pseudoephedrine hydrochloride and 600 mg guaifenesin in an extended-release formulation intended for oral administration. Inactive ingredients: calcium phosphate dibasic, hydroxypropyl methylcellulose, lactose, lake blue No. 1 FD&C, magnesium stearate, povidone, silicon dioxide colloidal, and stearic acid.

Guaifenesin is an expectorant. Chemically, it is 3-(2-methoxyphe-noxy)-1, 2-propanediol and has the following structural formula:

Guaifenesin  Structural Formula Illustration

Pseudoephedrine hydrochloride is a nasal decongestant. Chemically, it is [S-(R*,R*)]-α-[1-(methylamino)ethyl] benzen-emethanol hydrochloride and has the following structural formula:

Pseudoephedrine hydrochloride   Structural Formula Illustration

What are the possible side effects of guaifenesin and pseudoephedrine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • increased blood pressure (severe...

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What are the precautions when taking guaifenesin pseudoephedrine extended-release tablets (Guaifenex PSE 60)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to pseudoephedrine or guaifenesin; or if you have any other allergies. Also tell your doctor if you have had a bad reaction to similar drugs (sympathomimetics such as ephedrine, phenylephrine). This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as emphysema, chronic bronchitis, asthma, smoker's cough), cough with blood or large amounts of mucus, high blood pressure, heart disease (such as chest pain, heart failure, heart attack), fast/slow/irregular heartbeat, diabetes, a certain eye...

Read All Potential Precautions of Guaifenex PSE 60 »

Last reviewed on RxList: 8/5/2008
This monograph has been modified to include the generic and brand name in many instances.

Guaifenex PSE 60 - User Reviews

Guaifenex PSE 60 User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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