home > drugs a-z list > guanfacine hydrochloride (guanfacine) drug center

Recommended Topic Related To:

Guanfacine Hydrochloride

High blood pressure facts

  • High blood pressure (hypertension) is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mm Hg.
  • High blood pressure is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs.
  • Poorly controlled high blood pressure ultimately can cause damage to blood vessels in the eye, thickening of the heart muscle and heart attacks, hardening of the arteries (arteriosclerosis), kidney failure, and strokes.
  • Most antihypertensive medications can be used alone or in combination. Some are used only in combination. Some are preferred over others in certain specific medical situations. And some are not to be used (contraindicated) in other situations.
  • Several classes of antihypertensive medications are available, including ACE i...

Guanfacine Hydrochloride

font size

Guanfacine Hydrochloride Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Guanfacine hydrochloride (Brand Name: Tenex) is used to treat high blood pressure (hyptertension). It is a centrally acting antihypertensive with a2-adrenoceptor agonist properties. This medication is available in generic form. Common side effects include dry mouth, sedation, weakness, dizziness, constipation, and impotence.

The recommended initial dose of guanfacine hydrochloride when given alone or in combination with another antihypertensive drug is 1 mg daily at bedtime to minimize drowsiness. A doctor may increase dosage until the desired result is obtained. Guanfacine hydrochloride may interact with valproic acid, drugs affecting liver enzymes that remove guanfacine from your body (e.g., azole antifungals, rifamycins), products that cause drowsiness, including alcohol, antihistamines, drugs for sleep or anxiety, muscle relaxants, narcotics, cough-and-cold products, diet aids, or non-steroidal anti-inflammatory drugs (NSAIDs). Guanfacine hydrochloride should be used during pregnancy only if prescribed. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding. Stopping guanfacine hydrochloride suddenly could cause severe high blood pressure, anxiety, and other side effects.

Our Guanfacine hydrochloride Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Guanfacine Hydrochloride Prescribing Information: Indications & Dosage

Guanfacine Hydrochloride structural formula illustration

Guanfacine hydrochloride (guanfacine) tablets are indicated in the management of hypertension. Guanfacine may be given alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.

Read the complete drug monograph for Guanfacine Hydrochloride »

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Hypertension

Get tips on handling your hypertension.