"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
(guanfacine hydrochloride) Tablet
Guanfacine hydrochloride (guanfacine) is a centrally acting antihypertensive with a2-adrenoceptor agonist properties in tablet form for oral administration.
The chemical name of guanfacine hydrochloride (guanfacine) is N-Amidino-2-(2,6-dichlorophenyl) acetamide monohydrochloride and its molecular weight is 282.55. Its structural formula is:
Guanfacine hydrochloride (guanfacine) is a white to off-white powder; sparingly soluble in water and alcohol and slightly soluble in acetone.
Each tablet, for oral administration, contains guanfacine hydrochloride equivalent to 1 mg or 2 mg guanfacine. The tablets contain the following inactive ingredients:
1 mg - anhydrous lactose, FD&C Red 40 aluminum lake, microcrystalline cellulose,
povidone, stearic acid.
2 mg - anhydrous lactose, D&C Yellow 10 aluminum lake, FD&C Red 40 aluminum lake, microcrystalline cellulose, povidone, stearic acid.
Last reviewed on RxList: 12/6/2007
This monograph has been modified to include the generic and brand name in many instances.
Additional Guanfacine Hydrochloride Information
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