Halaven
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Halaven
HALAVEN®
(eribulin mesylate)
DRUG DESCRIPTION
HALAVEN (eribulin mesylate) Injection is a non-taxane
microtubule dynamics inhibitor. Eribulin mesylate is a synthetic analogue of
halichondrin B, a product isolated from the marine sponge
Halichondria okadai. The chemical name for eribulin mesylate is 11,15:18,21:24,28Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3b][1,4]dioxacyclopentacosin-5(4H)-one,
2-[(2S)-3-amino-2-hydroxypropyl]hexacosahydro-3methoxy-26-methyl-20,27-bis(methylene)-,
(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-,
methanesulfonate (salt). It has a molecular weight of 826.0 (729.9 for free
base). The empirical formula is C40H59NO11•CH4O3S.
Eribulin mesylate has the following structural formula:
 |
HALAVEN is a clear, colorless, sterile solution for intravenous administration. Each vial contains 1 mg of eribulin mesylate as a 0.5 mg/mL solution in ethanol: water (5:95).
What are the possible side effects of eribulin (Halaven)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fever, chills, body aches, flu symptoms, sores in your mouth and throat;
- pain or burning when you urinate;
- pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
- severe numbness or tingling in your hands and feet;
- low potassium (confusion, uneven heart rate, extreme thirst,...
Read All Potential Side Effects and See Pictures of Halaven »
Last reviewed on RxList: 3/2/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Halaven Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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