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HALAVEN (eribulin mesylate) Injection is a non-taxane
microtubule dynamics inhibitor. Eribulin mesylate is a synthetic analogue of
halichondrin B, a product isolated from the marine sponge
Halichondria okadai. The chemical name for eribulin mesylate is 11,15:18,21:24,28Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3b][1,4]dioxacyclopentacosin-5(4H)-one,
methanesulfonate (salt). It has a molecular weight of 826.0 (729.9 for free
base). The empirical formula is C40H59NO11•CH4O3S.
Eribulin mesylate has the following structural formula:
HALAVEN is a clear, colorless, sterile solution for intravenous administration. Each vial contains 1 mg of eribulin mesylate as a 0.5 mg/mL solution in ethanol: water (5:95).
Last reviewed on RxList: 3/2/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Halaven Information
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