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Primary hyperparathyroidism is a disorder of the parathyroid glands, also called parathyroids. "Primary" means this disorder originates in the parathyroids: One or more enlarged, overactive parathyroid glands secretes too much parathyroid hormone (PTH). In secondary hyperparathyroidism, a problem such as kidney failure causes the parathyroids to be overactive. This publication focuses on primary hyperparathyroidism.
The parathyroid glands are four pea-sized glands located on the thyroid gland in the neck. Occasionally, a person is born with one or more of the parathyroid glands embedded in the thyroid, in the thymus, or located elsewhere around this area. In most such cases, however, the glands function normally.
Though their names are similar, the thyroid and parathyroid glands are entirely different glands, each producing distinct hormones with specific functions. The p...
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IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
DOXERCALCIFEROL - ORAL
(dox-er-kal-SIF-e-role)
COMMON BRAND NAME(S): Hectorol
USES: This medication is used to treat people with serious kidney disease who have high levels of a certain natural substance (parathyroid hormone-PTH), which your body normally makes. High PTH levels affect the balance of other minerals in your body (calcium and phosphorus) and may result in weak bones. Doxercalciferol is a man-made form of vitamin D. It works by decreasing PTH levels and increasing calcium/phosphorus levels in the body.
HOW TO USE: Take this medication by mouth with or without food, usually 3 times a week on dialysis days (e.g., Monday, Wednesday, Friday) or as directed by your doctor.
Dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose or temporarily stop this drug based on laboratory test results (PTH levels). Do not increase your dose, take it more frequently, or stop taking this medication without your doctor's approval.
It is very important to follow the diet recommended by your doctor to get the most benefit from this medication and to prevent serious side effects. Do not take more than 2 grams of calcium a day while you are taking this medication. Sources of calcium include your diet, phosphate binders, or calcium supplements. If you have any questions about how much calcium you take in a day, ask your doctor or pharmacist. Do not take other supplements/vitamins (such as vitamin D) unless otherwise directed by your doctor. (See also Drug Interactions section.)
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day that you have a prescribed dose.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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