Herceptin (Trastuzumab) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Herceptin

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Breast cancer facts

Breast cancer is the most common cancer among American women.
One in every eight women in the United States develops breast cancer.
There are many types of breast cancer that differ in their capability of spreading (metastasize) to other body tissues.
The causes of breast cancer are not yet fully known although a number of risk factors have been identified.
There are many different types of breast cancer.
Breast cancer is diagnosed with physician and self-examination of the breasts, mammography, ultrasound testing, and biopsy.
Treatment of breast cancer depends on the type of cancer and its stage (the extent of spread in the body).

According to the American Cancer society:

Over 200,000 new cases of invasive breast cancer are diagnosed each year.
Nearly 40,000 women will die of breast cancer in 2011.
There are over 2...

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PATIENT INFORMATION

Advise patients to contact a health care professional immediately for any of the following: new onset or worsening shortness of breath, cough, swelling of the ankles/legs, swelling of the face, palpitations, weight gain of more than 5 pounds in 24 hours, dizziness or loss of consciousness [see Boxed Warning Cardiomyopathy].

Advise pregnant women and women of childbearing potential that Herceptin (trastuzumab) exposure can result in fetal harm [see WARNINGS AND PRECAUTIONS and Use in Specific Populations].

Advise women of childbearing potential to use effective contraceptive methods during treatment and for a minimum of six months following Herceptin [see WARNINGS AND PRECAUTIONS].

Advise nursing mothers treated with Herceptin (trastuzumab) to discontinue nursing or discontinue Herceptin (trastuzumab) , taking into account the importance of the drug to the mother [see Use In Specific Populations].

Encourage women who are exposed to Herceptin (trastuzumab) during pregnancy to enroll in MotHER- the Herceptin (trastuzumab) Pregnancy Registry (1-800-690-6720) [see WARNINGS AND PRECAUTIONS and Use In Specific Populations].

Last reviewed on RxList: 11/23/2010
This monograph has been modified to include the generic and brand name in many instances.