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Hexalen

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Hexalen




Overdosage
Contraindications

OVERDOSE

No case of acute overdosage in humans has been described. The oral LD50 dose in rats was 1050 mg/kg and 437 mg/kg in mice.

CONTRAINDICATIONS

HEXALEN® (altretamine) capsules is contraindicated in patients who have shown hypersensitivity to it. HEXALEN® (altretamine) capsules should not be employed in patients with preexisting severe bone marrow depression or severe neurologic toxicity. HEXALEN® (altretamine) capsules has been administered safely, however, to patients heavily pretreated with cisplatin and/or alkylating agents, including patients with preexisting cisplatin neuropathies. Careful monitoring of neurologic function in these patients is essential.

Last reviewed on RxList: 10/9/2008
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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Hexalen - User Reviews

Hexalen User Reviews

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