"The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).
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Patients should inform their health care practitioner if they have one or more of the following:
- Inform your physician if you are pregnant. (See PRECAUTIONS – Pregnancy)
- Inform your physician if you are allergic to any drugs or food, or if you have immune, autoimmune, or immune deficiency disorders. Also, inform your physician if you had any reactions to previous injections of dyes used for x-ray procedures. (See PRECAUTIONS – General)
- Inform your physician of all medications you are currently taking, including non-prescription drugs (over-the-counter), before you have this procedure.
Patients should be advised to follow radiation safety precautions after receiving Sodium Iodide I-131 treatment to minimize the radiation contamination of other persons or the environment:
- Patients who receive Sodium Iodide I-131 should be advised that for several hours following administration, radioactivity will be present in excreted urine. To help protect themselves and others in their environment, precautions need to be taken for 12 hours following administration.
- Whenever possible, a toilet should be used rather than a urinal, and the toilet should be flushed several times after each use. Spilled urine should be cleaned up completely and patients should wash their hands thoroughly.
- If blood or urine gets into clothing, the clothing should be washed separately, or stored for 1 to 2 weeks to allow for decay of the I-131.
- Increase intake of fluids to promote more frequent voiding to help eliminate radioactive iodide.
- Avoid close or prolonged contact with others, especially children and pregnant women; sleep alone; avoid intimate contact.
- Wash sink and tub after use; use separate towels and washcloths; launder clothes and linen separately. Avoid handling another person's eating or drinking utensils, toothbrushes, and personal hygiene materials.
Last reviewed on RxList: 10/6/2011
This monograph has been modified to include the generic and brand name in many instances.
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