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"The U.S. Food and Drug Administration today approved Cometriq (cabozantinib) to treat medullary thyroid cancer that has spread to other parts of the body (metastasized).

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OVERDOSE

In the treatment of hyperthyroidism, over-dosage may result in hypothyroidism, the onset of which may be delayed. Appropriate replacement therapy is recommended if hypothyroidism occurs. Radiation absorbed doses to various tissues for any administered dose may be calculated by reference to Table 4 (Absorbed Radiation Doses I-131). (SeebCONTRAINDICATIONS, WARNINGS, PRECAUTIONS sections).

CONTRAINDICATIONS

Patients with vomiting and diarrhea should not receive radio-iodide and concurrent antithyroid therapy should be discontinued 3 to 4 days before administration of radioiodide.

Sodium Iodide I-131 is contraindicated in women who are, or who may become pregnant. (See Pregnancy section and Nursing section).

Last reviewed on RxList: 10/6/2011
This monograph has been modified to include the generic and brand name in many instances.

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