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Side Effects


Adverse events associated with the class of Sodium Iodide I-131 drug product include hypersensitivity reactions, radiation toxicities, and metabolic events.

Immediate adverse reactions typically are related to hypersensitivity; e.g., anaphylaxis, rash, hives, bronchospasm, and other allergic events.

Radiation adverse events are related to the dose include the following:

Bone marrow depression, leukopenia, thrombocytopenia, acute leukemia, anemia, blood dyscrasia, chromosomal abnormalities, radiation sickness, and death. Delayed radiation toxicity includes radiation thyroiditis, gastritis and sialadentis.

Metabolic adverse events include hypothyroidism and exaggerated hyperthyroidism due to radiation thyroiditis.

Tenderness and swelling of the neck, pain on swallowing, sore throat and cough may occur about the 3rd day after treatment.

Drug Abuse And Dependence

Patients administered Sodium Iodide I 131 Solution USP are not at risk for developing chemical dependency.

Read the Hicon (sodium iodide i 131) Side Effects Center for a complete guide to possible side effects


No information provided.

Last reviewed on RxList: 10/6/2011
This monograph has been modified to include the generic and brand name in many instances.

Side Effects

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