"The U.S. Food and Drug Administration today approved Zerbaxa (ceftolozane/tazobactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI).
(methenamine hippurate) Tablets USP
To reduce the development of drug-resistant bacteria and maintain the effectiveness of HIPREX (methenamine hippurate tablets USP) and other antibacterial drugs, HIPREX (methenamine hippurate) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Each yellow capsule-shaped tablet contains 1 g Methenamine Hippurate which is the Hippuric Acid Salt of Methenamine (hexamethylene tetramine). The tablet also contains inactive ingredients. FD&C Yellow No. 5 (tartrazine, see PRECAUTIONS), Magnesium Stearate, Povidone, and Saccharin Sodium.
What are the possible side effects of methenamine (Hiprex, Mandelamine, Urex)?
If you experience any of the following serious side effects, stop taking methenamine and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives;
- lower back or side pain;
- blood in urine; or
- increasingly painful or difficult urination.
Other, less serious side effects may be more likely to occur. Continue to take methenamine and talk to your doctor if you experience
- nausea or upset...
What are the precautions when taking methenamine hippurate (Hiprex)?
Before taking methenamine, tell your doctor or pharmacist if you are allergic to it; or to formaldehyde; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, dehydration.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and the effect on a...
Last reviewed on RxList: 8/14/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Hiprex Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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