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- Clinician Information:
Hismanal Patient Information including If I Miss a Dose
In this Article
- What is astemizole (Hismanal)?
- What are the possible side effects of astemizole (Hismanal)?
- What is the most important information I should know about astemizole (Hismanal)?
- Who should not take astemizole (Hismanal)?
- How should I take astemizole (Hismanal)?
- What happens if I miss a dose (Hismanal)?
- What happens if I overdose (Hismanal)?
- What should I avoid while taking astemizole (Hismanal)?
- What other drugs will affect astemizole (Hismanal)?
- Where can I get more information?
What happens if I miss a dose (Hismanal)?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose (Hismanal)?
Seek emergency medical attention.
Symptoms of an astemizole overdose include headache, drowsiness, irregular heartbeats, nausea, and vomiting.
What should I avoid while taking astemizole (Hismanal)?
Use caution when driving, operating machinery, or performing other hazardous activities. Astemizole may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking astemizole.
Do not take astemizole with grapefruit or grapefruit juice. Grapefruit products may increase amount of astemizole available in your body, which could lead to dangerous side effects.
What other drugs will affect astemizole (Hismanal)?
You cannot take astemizole if you are taking any of the following medicines:
- an antifungal drug including ketoconazole (Nizoral) or itraconazole (Sporanox);
- an antibiotic including erythromycin (E.E.S., E-Mycin, Ery-Tab), clarithromycin (Biaxin), or troleandomycin (TAO);
- the malaria medicine quinine (Quinamm); or
- the medicine nefazodone (Serzone).
A dangerous side effect involving irregular heartbeats could occur if you take astemizole with any of the medicines listed above.
Before taking this medication, tell your doctor if you are taking any of the following medicines:
- an antifungal including fluconazole (Diflucan), miconazole (Monistat), or metronidazole (Flagyl);
- a selective serotonin reuptake inhibitor (SSRI) including fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft);
- a protease inhibitor including amprenavir (Agenerase), ritonavir (Norvir), indinavir (Crixivan), saquinavir (Invirase, Fortovase), or nelfinavir (Viracept); or
- zileuton (Zyflo).
You may not be able to take astemizole, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with astemizole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
Your pharmacist has additional information about astemizole written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Hismanal Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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