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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Hismanal Patient Information including If I Miss a Dose

What happens if I miss a dose (Hismanal)?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose (Hismanal)?

Seek emergency medical attention.

Symptoms of an astemizole overdose include headache, drowsiness, irregular heartbeats, nausea, and vomiting.

What should I avoid while taking astemizole (Hismanal)?

Use caution when driving, operating machinery, or performing other hazardous activities. Astemizole may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking astemizole.

Do not take astemizole with grapefruit or grapefruit juice. Grapefruit products may increase amount of astemizole available in your body, which could lead to dangerous side effects.

What other drugs will affect astemizole (Hismanal)?

You cannot take astemizole if you are taking any of the following medicines:

  • an antifungal drug including ketoconazole (Nizoral) or itraconazole (Sporanox);
  • an antibiotic including erythromycin (E.E.S., E-Mycin, Ery-Tab), clarithromycin (Biaxin), or troleandomycin (TAO);
  • the malaria medicine quinine (Quinamm); or
  • the medicine nefazodone (Serzone).

A dangerous side effect involving irregular heartbeats could occur if you take astemizole with any of the medicines listed above.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

  • an antifungal including fluconazole (Diflucan), miconazole (Monistat), or metronidazole (Flagyl);
  • a selective serotonin reuptake inhibitor (SSRI) including fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft);
  • a protease inhibitor including amprenavir (Agenerase), ritonavir (Norvir), indinavir (Crixivan), saquinavir (Invirase, Fortovase), or nelfinavir (Viracept); or
  • zileuton (Zyflo).

You may not be able to take astemizole, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with astemizole. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has additional information about astemizole written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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