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- Clinician Information:
Hivid Patient Information including How Should I Take
In this Article
- What is zalcitabine (Hivid)?
- What are the possible side effects of zalcitabine (Hivid)?
- What is the most important information I should know about zalcitabine (Hivid)?
- What should I discuss with my healthcare provider before taking zalcitabine (Hivid)?
- How should I take zalcitabine (Hivid)?
- What happens if I miss a dose (Hivid)?
- What happens if I overdose (Hivid)?
- What should I avoid while taking zalcitabine (Hivid)?
- What other drugs will affect zalcitabine (Hivid)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking zalcitabine (Hivid)?
Do not use this medication if you are allergic to zalcitabine.
Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:
- kidney disease;
- liver disease (including hepatitis B);
- a history of pancreatitis; or
- if you have used a medicine similar to zalcitabine in the past, such as abacavir (Ziagen), didanosine (Videx), lamivudine (Epivir), stavudine (Zerit), tenofovir (Viread), or zidovudine (Retrovir).
If you have any of the conditions listed above, you may not be able to use zalcitabine or you may need a dosage adjustment or special tests during treatment.
Zalcitabine may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Call your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal.
Zalcitabine can also cause severe or life-threatening effects on your liver or pancreas. Call your doctor at once if you have any of these symptoms while taking zalcitabine: severe pain in your upper stomach spreading to your back, fast heart rate, nausea and vomiting, diarrhea, loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant.
Your name may need to be listed on an antiviral pregnancy registry when you start using zalcitabine. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether zalcitabine had any effect on the baby.
You should not breast-feed while you are using zalcitabine. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.
How should I take zalcitabine (Hivid)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Take zalcitabine with a full glass of water.
Zalcitabine is usually taken every 8 hours, but if you have kidney disease you may need to take it every 12 or 24 hours. Follow your doctor's instructions.
Take zalcitabine on an empty stomach, at least 1 hour before or 2 hours after a meal. This will make it easier for your body to absorb the medicine.
It is important to use zalcitabine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
Store zalcitabine in a tightly closed container at room temperature away from moisture and heat.
Additional Hivid Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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