April 30, 2017
Recommended Topic Related To:

H.P. Acthar Gel

"Among people with early-stage multiple sclerosis (MS), those with higher blood levels of vitamin D had better outcomes during 5 years of follow-up. Identifying and correcting vitamin D insufficiency could aid in the early treatment of MS.


H.P. Acthar Gel

H.P. Acthar Gel Patient Information including How Should I Take

What should I discuss with my healthcare provider before using corticotropin (H.P. Acthar Gel)?

You should not use this medication if you have:

  • adrenal insufficiency (Addison's disease);
  • scleroderma;
  • a fungal infection anywhere in your body;
  • herpes infection of the eyes;
  • osteoporosis;
  • past or present stomach ulcer;
  • congestive heart failure;
  • high blood pressure;
  • if you have recently had surgery; or
  • if you are allergic to pork proteins.

Corticotropin can worsen an infection you already have, or reactivate an infection you recently had. Before using this medication, tell your doctor about any illness or infection you have had within the past several weeks.

Other medical conditions you should tell your doctor about before using corticotropin include:

  • liver disease (such as cirrhosis);
  • kidney disease;
  • a thyroid disorder;
  • diabetes;
  • a history of tuberculosis;
  • a muscle disorder such as myasthenia gravis;
  • glaucoma or cataracts;
  • depression or mental illness; or
  • a stomach or intestinal disorder.

If you have any of these conditions, you may need a dose adjustment or special tests to safely use corticotropin.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether corticotropin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How is corticotropin given (H.P. Acthar Gel)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

Corticotropin is given as an injection into a muscle or under the skin. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

When used as in treating a medical condition, corticotropin is sometimes given daily, or every 2 to 3 days. Follow your doctor's instructions.

Do not inject corticotropin into a vein.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Your medication needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using corticotropin.

If you use corticotropin at home, store it in the refrigerator and do not allow it to freeze. You may allow the medication to reach room temperature before measuring your dose in a syringe. Then place the vial back in the refrigerator.

Side Effects Centers

Additional H.P. Acthar Gel Information

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Multiple Sclerosis

Get the latest treatment options.