"Real-world rates of severe hypoglycemia among certain subgroups of patients with diabetes are considerably higher than those seen in randomized clinical trials, a new analysis shows.
The findings were published online December 17 in "...
Humalog Mix 50-50
Humalog Mix 50-50 Patient Information including How Should I Take
In this Article
- What is insulin lispro and insulin lispro protamine (Humalog Mix 50-50)?
- What are the possible side effects of insulin lispro and insulin lispro protamine?
- What is the most important information I should know about insulin lispro and insulin lispro protamine?
- What should I discuss with my healthcare provider before using insulin lispro and insulin lispro protamine?
- How should I use insulin lispro and insulin lispro protamine?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while using insulin lispro and insulin lispro protamine?
- What other drugs will affect insulin lispro and insulin lispro protamine?
- Where can I get more information?
What should I discuss with my healthcare provider before using insulin lispro and insulin lispro protamine?
Do not use this medication if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar).
To make sure you can safely use insulin lispro and insulin lispro protamine, tell your doctor if you have liver or kidney disease.
Tell your doctor about all other medications you use, including any oral (by mouth) diabetes medications.
Insulin is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether insulin lispro and insulin lispro protamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use insulin lispro and insulin lispro protamine?
Insulin is injected under the skin. You will be shown how to use injections at home. Do not self inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
Use this medication within 15 minutes before eating a meal.
Insulin lispro and insulin lispro protamine should appear cloudy after mixing. Do not use the medication if it has changed colors or has any particles in it. Return the medication to your pharmacy for a new supply.
Use a different place on your injection skin area each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Never share an injection pen or cartridge with another person. Sharing injection pens or cartridges can allow disease such as hepatitis or HIV to pass from one person to another.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremors, irritability, or trouble concentrating.
Also watch for signs of blood sugar that is too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.
Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.
Ask your doctor how to adjust your insulin dose if needed. Do not change your medication dose or schedule without your doctor's advice.
Wear a medical alert tag or carry an ID card stating that you have diabetes. Any medical care provider who treats you should know that you are diabetic.
Storing unopened vials or injection pens: Keep in the carton and store in a refrigerator, protected from light. Throw away any insulin not used before the expiration date on the medicine label.
Unopened vials may also be stored at room temperature for up to 28 days, away from heat and bright light. Throw away any insulin not used within 28 days.
Unopened injection pens may also be stored at room temperature for up to 10 days, away from heat and bright light. Throw away any insulin not used within 10 days.
Storing after your first use: You may keep "in-use" vials in the refrigerator, protected from light. Use within 28 days.
Do not refrigerate an in-use injection pen. Keep it at room temperature and use within 10 days.
Do not freeze insulin lispro and insulin lispro protamine, and throw away the medication if it has become frozen.
Additional Humalog Mix 50-50 Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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