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Humalog Mix 50-50
Humalog 50-50 Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Humalog Mix 50/50 (50% insulin lispro protamine suspension and 50% insulin lispro injection (rDNA ORIGIN) is a hormone produced in the body used to treat type 1 (insulin-dependent) diabetes in adults. Humalog Mix 50/50 is usually given together with another long-acting insulin. Common side effects of Humalog Mix 50/50 include pain, redness, swelling or itching at the injection site. These side effects usually go away after a few days or weeks. The most common side effect of insulin products such as Humalog Mix 50/50 is low blood sugar (hypoglycemia), Symptoms of low blood sugar include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure.
Dosage regimens of Humalog Mix50/50 vary among patients and are determined by the physician familiar with the patient's metabolic needs, eating habits, and other lifestyle variables. Humalog Mix 50/50 may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. Other medicines can increase or decrease the effects of insulin on lowering blood sugar. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant before using Humalog Mix 50/50. Discuss a plan for managing blood sugars with your doctor before becoming pregnant. Your doctor may switch the type of insulin you use during pregnancy. It is unknown if this drug passes into breast milk. Insulin needs may change while breastfeeding. Consult your doctor before breastfeeding.
Our Humalog Mix 50/50 (50% insulin lispro protamine suspension and 50% insulin lispro injection (rDNA ORIGIN) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Humalog 50-50 in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of insulin allergy: itching skin rash over the entire body, wheezing, trouble breathing, fast heart rate, sweating, or feeling like you might pass out.
Hypoglycemia, or low blood sugar, is the most common side effect of insulin. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets with you in case you have low blood sugar.
Insulin lispro and insulin lispro protamine can also cause hypokalemia (low potassium levels in the blood). Call your doctor at once if you have symptoms such as confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling.
Tell your doctor if you have itching, swelling, redness, or thickening of the skin where you inject insulin lispro and insulin lispro protamine.
Read the entire detailed patient monograph for Humalog 50-50 (Insulin Lispro)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Humalog 50-50 Overview - Patient Information: Side Effects
Pain, redness, swelling or itching at the injection site may occur. These effects usually go away after a few days or weeks. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Too much insulin can cause low blood sugar (hypoglycemia). This effect may also occur if you do not consume enough calories. The symptoms include chills, cold sweats, blurred vision, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands/feet, or hunger. It is a good habit to carry glucose (sugar) tablets or gel to treat low blood sugar. If you don't have these reliable forms of glucose, raise your blood sugar quickly by eating a quick source of sugar such as table sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Tell your doctor immediately about the reaction. To help prevent low blood sugar, eat meals on a regular schedule and do not skip meals.
Too little insulin can cause high blood sugar (hyperglycemia). Symptoms of high blood sugar include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor. If these symptoms occur, tell your doctor immediately. Your treatment plan may need to be changed.
This medication may cause low potassium levels in the blood (hypokalemia). Tell your doctor immediately if any of these unlikely but serious side effects occur: muscle cramps, weakness, irregular heartbeat.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following signs of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Humalog 50-50 (Insulin Lispro)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Humalog 50-50 FDA Prescribing Information: Side Effects
Clinical studies comparing Humalog Mix50/50 with human insulin mixtures did not demonstrate a difference in frequency of adverse events between the two treatments. Adverse events commonly associated with human insulin therapy include the following:
Body as a Whole - allergic reactions (see PRECAUTIONS).
Read the entire FDA prescribing information for Humalog 50-50 (Insulin Lispro)
Additional Humalog Mix 50-50 Information
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