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Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other insulin products (e.g., insulin aspart, NPH), oral diabetes medicine (e.g., glyburide, pioglitazone), ACE inhibitors (e.g., enalapril, lisinopril), clonidine, corticosteroids (e.g., prednisone), danazol, disopyramide, estrogens and progestins (including birth control pills), fibrates (e.g., clofibrate, gemfibrozil), fluoxetine, guanethidine, isoniazid, lithium, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), niacin, pentamidine, pentoxifylline, propoxyphene, protease inhibitors (e.g., indinavir, ritonavir), anti-psychotic drugs (e.g., phenothiazines such as chlorpromazine, atypical anti-psychotics such as clozapine and olanzapine), quinolone antibiotics (e.g., ciprofloxacin), reserpine, salicylates (e.g., aspirin), somatropin, sulfa antibiotics (e.g., sulfamethoxazole), sympathomimetic drugs (e.g., albuterol, epinephrine), thyroid medicine, "water pills" (diuretics such as furosemide, hydrochlorothiazide).

Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that could affect your blood sugar. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include headache, sweating, shakiness, increased hunger, vision changes, nervousness, tiredness, seizures, loss of consciousness.

NOTES: Do not share this medication with others.

It is recommended you attend a diabetes education program to understand diabetes and all the important aspects of its treatment, including meals/diet, exercise, personal hygiene, medications, and getting regular eye, foot and medical exams.

Keep all medical appointments. Laboratory and/or medical tests (e.g., liver and kidney function tests, fasting blood glucose, hemoglobin A1c, complete blood counts) should be performed periodically to monitor for side effects and response to therapy.

Wear or carry identification stating that you have diabetes and are using this drug. See Medical Alert section.

MISSED DOSE: It is very important to follow your insulin regimen exactly. Do not miss any doses of insulin. Discuss specific instructions with your doctor now in case you miss a dose of insulin in the future.

STORAGE: It is best to refrigerate the unopened vial/cartridge between 36-46 degrees F (2-8 degrees C). Once opened, this medication may be stored in the refrigerator or at room temperature below 86 degrees F (30 degrees C). Store in the carton to protect from light. Depending on your brand, discard the vial either 28 days or 42 days after opening. Check with your pharmacist regarding your specific brand. Do not freeze. Discard the insulin if it has been frozen.

If using this drug in an insulin pump, do not store this drug in the pump for more than 48 hours. Doing so may lead to ineffective therapy and high blood sugars. Do not expose the insulin in your pump to direct sunlight or temperatures above 98.6 degrees F (37 degrees C).

Protect insulin from direct sunlight, heat, and moisture. Keep all medicines away from children and pets.

Keep extra supplies of insulin, syringes, and needles on hand.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

Information last revised August 2010 Copyright(c) 2010 First DataBank, Inc.