November 26, 2015
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  • Bone Marrow Suppression
    Inform patients that HYCAMTIN decreases blood cell counts such as white blood cells, platelets, and red blood cells. Advise patients to notify their healthcare provider promptly for fever, other signs of infection (e.g., chills, cough, or burning pain on urination), or bleeding. Inform patients that frequent blood tests will be performed while taking HYCAMTIN to monitor for the occurrence of bone marrow suppression.
  • Embryofetal Toxicity
    Advise patients to contact their healthcare provider if they become pregnant, or if pregnancy is suspected during treatment with HYCAMTIN. Advise females of reproductive potential to use effective contraception during treatment and for 1 month after the last dose of HYCAMTIN. Advise males with a female sexual partner of reproductive potential to use effective contraception during treatment and for 3 months after the last dose of HYCAMTIN [see WARNINGS AND PRECAUTIONS, Use In Specific Populations].
  • Lactation
    Advise nursing mothers to discontinue breastfeeding during treatment with HYCAMTIN [see Use In Specific Populations].
  • Infertility
    Advise male and female patients of the potential risk for impaired fertility and possible family planning options [see Use in Specific Populations].
  • Asthenia and Fatigue
    Advise patients that HYCAMTIN may cause asthenia or fatigue. These symptoms may impair the ability to safely drive or operate machinery.

Last reviewed on RxList: 6/19/2015
This monograph has been modified to include the generic and brand name in many instances.

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