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There is no known antidote for overdosage with HYCAMTIN capsules. The primary anticipated complication of overdosage would consist of hematological toxicity. The patient should be observed closely for bone marrow suppression, and supportive measures (such as the prophylactic use of G-CSF and/or antibiotic therapy) should be considered.
HYCAMTIN is contraindicated in patients who have a history of severe hypersensitivity reactions (e.g., anaphylactoid reactions) to topotecan or to any of its ingredients. HYCAMTIN should not be used in patients with severe bone marrow depression.
Last reviewed on RxList: 10/28/2011
This monograph has been modified to include the generic and brand name in many instances.
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